ORF name	Slide_Ave_Signal(before GST)	Pro_pro interaction	Known substrate	localization	Essentiality	MIPS annotation	Common name	SGD annotation
YMR304W	2131.96	0	0	cytoplasm	Non-essen Genes	-	UBP15	cytoplasm	ubiquitin-specific protease	protein deubiquitination
YGL153W	2758.5	0	0	peroxisome	Non-essen Genes	-	PEX14	peroxisomal membrane	peroxisomal membrane	protein binding	protein-peroxisome targeting	protein-peroxisome targeting	protein-peroxisome targeting
YLL018C	1187.25	0	0	cytoplasm	Essentail Genes	-	DPS1	cytoplasm	aspartate-tRNA ligase	protein biosynthesis
YGR240C	750.25	0	0	cytoplasm	Non-essen Genes	-	PFK1	6-phosphofructokinase complex	cytoplasm	6-phosphofructokinase	glycolysis
YDR312W	1632.73	0	0	nucleolus && nucleus	Non-essen Genes	-	SSF2	nucleolus	rRNA binding	conjugation with cellular fusion	ribosomal large subunit assembly and maintenance	ribosomal large subunit assembly and maintenance
YFR021W	1359.07	0	0	Ambiguous	Non-essen Genes	-	AUT10	cytosol	molecular_function unknown	autophagy	autophagy	protein-vacuolar targeting	protein-vacuolar targeting	sporulation (sensu Saccharomyces)	sporulation (sensu Saccharomyces)	sporulation (sensu Saccharomyces)	vacuolar protein processing/maturation	vacuolar protein processing/maturation
YKR092C	2044	0	0	nucleolus	Non-essen Genes	-	SRP40	nucleolus	chaperone	nucleocytoplasmic transport
YER131W	7662.76	0	0	cytoplasm	Non-essen Genes	-	RPS26B	cytosolic small ribosomal subunit (sensu Eukarya)	structural constituent of ribosome	protein biosynthesis
YKR094C	2152.27	0	0	cytoplasm	Non-essen Genes	191.11	RPL40B	cytosolic large ribosomal subunit (sensu Eukarya)	protein tagging	structural constituent of ribosome	protein biosynthesis	ubiquitin-dependent protein catabolism
YCR027C	3711.29	0	0	cytoplasm	Non-essen Genes	61.21.41	RHB1	extrinsic to plasma membrane	RHEB small monomeric GTPase	arginine transport	arginine transport	lysine transport
YBL047C	1259.73	0	0	punctate composite	Non-essen Genes	-	EDE1	actin cortical patch (sensu Saccharomyces)	bud neck	bud tip	molecular_function unknown	endocytosis
YHR161C	4506.28	0	0	cell periphery && bud neck && Ambiguous	Non-essen Genes	-	YAP1801	actin cortical patch (sensu Saccharomyces)	cytoskeletal adaptor	cytoskeletal adaptor	endocytosis	endocytosis
YDR229W	2920.59	0	0	vacuolar membrane	Non-essen Genes	-	IVY1	vacuolar membrane (sensu Fungi)	phospholipid binding	secretory pathway	secretory pathway
YKR006C	475.75	0	0	mitochondrion	Non-essen Genes	-	MRPL13	mitochondrial large ribosomal subunit	structural constituent of ribosome	protein biosynthesis
YGL105W	3563.29	0	0	cytoplasm	Non-essen Genes	-	ARC1	cytoplasm	methionyl glutamyl tRNA synthetase complex	methionyl glutamyl tRNA synthetase complex	tRNA binding	tRNA binding	amino acid activation	tRNA-nucleus export
YGR159C	2322.75	0	0	nucleolus	Non-essen Genes	-	NSR1	nucleolus	nucleus	RNA binding	single-stranded DNA binding	rRNA processing	ribosomal small subunit assembly and maintenance
YDR354W	9513.67	0	0	cytoplasm && nucleus	Non-essen Genes	-	TRP4	cellular_component unknown	anthranilate phosphoribosyltransferase	tryptophan biosynthesis	tryptophan biosynthesis
YLR206W	7403.53	0	1	actin	Non-essen Genes	-	ENT2	actin cortical patch (sensu Saccharomyces)	cytoskeletal adaptor	actin cortical patch assembly	actin filament organization	endocytosis
YOR054C	5387.23	0	0	actin	Non-essen Genes	-	VHS3	cellular_component unknown	molecular_function unknown	G1/S transition of mitotic cell cycle
YNL227C	1217	0	0	cytoplasm	Non-essen Genes	201.21.21		cellular_component unknown	molecular_function unknown	endocytosis
YFR024C	8593.11	0	0	actin	Non-essen Genes	-	YSC85	cellular_component unknown	molecular_function unknown	biological_process unknown
YOR239W	8389.73	0	0	cytoplasm	Non-essen Genes	-	ABP140	actin filament	actin filament	actin cross-linking	actin cytoskeleton organization and biogenesis
YMR297W	2076.75	0	0	vacuole	Non-essen Genes	151	PRC1	cytoplasm	endoplasmic reticulum	carboxypeptidase C	vacuolar protein catabolism
YOR257W	2705.75	0	0	vacuole	Essentail Genes	-	CDC31	half bridge of spindle pole body	nuclear pore	structural constituent of cytoskeleton	microtubule nucleation	spindle pole body duplication (sensu Saccharomyces)
YPL223C	6560	0	0	cytoplasm	Non-essen Genes	-	GRE1	cytoplasm	molecular_function unknown	response to dessication	response to dessication	response to stress
YNL277W	1827.45	0	0	cytoplasm && nucleus	Non-essen Genes	-	MET2	cytoplasm	homoserine O-acetyltransferase	homoserine metabolism	methionine biosynthesis
YGR135W	3064.28	0	0	cytoplasm && nucleus	Non-essen Genes	-	PRE9	20S core proteasome complex	proteasome endopeptidase	ubiquitin-dependent protein catabolism
YGL207W	2127.25	0	0	nucleus	Essentail Genes	-	SPT16	alpha DNA polymerase:primase complex	chromatin	transcription elongation factor complex	Pol II transcription elongation factor	transcription elongation factor	RNA elongation from Pol II promoter	chromatin modeling	regulation of global transcription from Pol II promoter
YNL272C	16344.05	0	0	bud neck && cytoplasm && Ambiguous	Essentail Genes	-	SEC2	cytoplasmic vesicle	cytosol	guanyl-nucleotide exchange factor	exocytosis
YGL234W	1967	0	0	cytoplasm	Non-essen Genes	-	"ADE5,7"	cytoplasm	phosphoribosylamine-glycine ligase	phosphoribosylformylglycinamidine cyclo-ligase	purine base metabolism
YMR250W	2895.75	0	0	cytoplasm	Non-essen Genes	-	GAD1	cytoplasm	glutamate decarboxylase	glutamate decarboxylase	glutamate catabolism	glutamate catabolism	response to oxidative stress
YDR239C	3046.5	0	0	cytoplasm	Non-essen Genes	-		cellular_component unknown	molecular_function unknown	biological_process unknown
YGL172W	2698.08	0	0	nuclear periphery	Essentail Genes	-	NUP49	nuclear membrane	nuclear pore	structural molecule	NLS-bearing substrate-nucleus import	mRNA-binding (hnRNP) protein-nucleus import	mRNA-nucleus export	nuclear pore organization and biogenesis	protein-nucleus export	protein-nucleus import	rRNA-nucleus export	ribosomal large subunit nucleus export	ribosomal protein-nucleus import	snRNA-nucleus export	snRNP protein-nucleus import	tRNA splicing	tRNA-nucleus export
YJL084C	3890.52	0	0	cytoplasm	Non-essen Genes	-		cytoplasm	cyclin binding	biological_process unknown
YOR329C	12511.08	0	0	Ambiguous	Essentail Genes	-	SCD5	peripheral membrane protein of membrane fraction	molecular_function unknown	actin filament organization	endocytosis	protein secretion	protein secretion
YNL027W	4504.26	0	0	cytoplasm	Non-essen Genes	201.21.21	CRZ1	cytoplasm	nucleus	DNA binding	transcription factor	transcription factor	transcription factor	calcium-mediated signaling	calcium-mediated signaling	calcium-mediated signaling	"regulation of transcription, DNA-dependent"
YMR222C	1479.25	0	0	cytoplasm	Non-essen Genes	-	FSH2	cellular_component unknown	molecular_function unknown	biological_process unknown
YGR021W	707.75	0	0	mitochondrion	Non-essen Genes	-		cellular_component unknown	molecular_function unknown	biological_process unknown
YLR276C	9821.82	0	0	mitochondrion	Essentail Genes	-	DBP9	nucleolus	ATP dependent RNA helicase	35S primary transcript processing	ribosomal large subunit assembly and maintenance
YPL106C	1014.25	0	0	cytoplasm	Non-essen Genes	101.21.21	SSE1	cytoplasm	co-chaperone	protein folding
YHR015W	3322.77	0	0	cytoplasm	Non-essen Genes	-	MIP6	nuclear pore	RNA binding	mRNA-nucleus export
YKR009C	8325.19	0	0	cytoplasm	Non-essen Genes	-	FOX2	peroxisomal matrix	3-hydroxyacyl-CoA dehydrogenase	enoyl-CoA hydratase	fatty acid beta-oxidation
YIL091C	6873.99	0	0	nucleolus && nucleus	Essentail Genes	-		cellular_component unknown	molecular_function unknown	biological_process unknown